Botulism

A disease caused by potent protein NEUROTOXINS produced by CLOSTRIDIUM BOTULINUM which interfere with the presynaptic release of ACETYLCHOLINE at the NEUROMUSCULAR JUNCTION. Clinical features include abdominal pain, vomiting, acute PARALYSIS (including respiratory paralysis), blurred vision, and DIPLOPIA. Botulism may be classified into several subtypes (e.g., food-borne, infant, wound, and others). (From Adams et al., Principles of Neurology, 6th ed, p1208)

Also Known As:

Botulism, Toxico-Infectious; Clostridium botulinum Infection; Foodborne Botulism; Infant Botulism; Toxico-Infectious Botulism; Wound Botulism; Botulism, Foodborne; Botulism, Infant; Botulism, Toxico Infectious; Botulism, Wound; Clostridium botulinum Infections; Foodborne Botulisms; Infant Botulisms; Infantile Botulism; Infection, Clostridium botulinum; Toxico Infectious Botulism; Wound Botulisms; Botulism, Infantile

Infections: 526564
- Bacterial Infections and Mycoses: 1
  - Bacterial Infections: 24368
    - Gram-Positive Bacterial Infections: 348
      - Clostridium Infections: 3461
        Botulism: 1444
Nervous System Diseases: 14178
- Neuromuscular Diseases: 2005
  - Neuromuscular Junction Diseases: 83
    - Botulism: 1444
- Neurotoxicity Syndromes: 299
  - Botulism: 1444
Chemically-Induced Disorders: 2
- Poisoning: 39310
  - Foodborne Diseases: 1935
    - Botulism: 1444

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Disease

Drug/Important Bio-Agent (IBA)